We aim to understand the mechanisms and genomics of RNA control, and its roles in biology and disease. All biological processes rely on precise control of the genetic material. The control of RNA, the immediate product of DNA, is vital. RNA-binding proteins (RBPs) dictate which mRNAs are regulated, and how, when and where that regulation occurs within a cell. The roles of RBPs and RNA in biology are incontrovertible: their dysfunctions cause disease, including cancer, epilepsy and obesity. The challenge now is to understand their molecular mechanisms and pathways to understand how they underlie key events in biology and disease.
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